The  Habana-Pinar del Río Highway crosses Artemisa  from northeast to southwest. This main road runs also through 6 municipalities. The  old Central Highway connects directly the municipal capitals of Bauta, Caimito, Guanajay, Candelaria and San Cristóbal with the provincial capital.

Artemisa occupies a central position in the territory, with excellent road communications with all the municipalities. It is located just  29 km from the center of the City of Havana.